GAZA CITY – Israel’s army and Gaza militants traded heavy cross-border fire Wednesday (10), with 22 Palestinians killed over two days amid the worst escalation of violence to hit the coastal territory in months.

Smoke billowed from the densely populated coastal enclave after Israel announced it was targeting rocket launch sites of the militant group Islamic Jihad.

Gaza’s health ministry said seven people were killed, a day after Israeli strikes on the Palestinian territory left 15 dead.

Sirens wailed in the Tel Aviv area warning of incoming rocket fire, an AFP journalist reported, and in communities close to the border, according to the army.

In a joint statement Palestinian militant factions said “hundreds of rockets” were fired, while the Israeli army reported 270 launches from Gaza.

Four of those killed Wednesday were fighters with the Popular Front for the Liberation of Palestine, the group said in a statement.

The fatalities also included a 10-year-old girl, whose body was seen by an AFP journalist in Gaza City’s Shifa hospital.

Prime Minister Benjamin Netanyahu said Israel was “ready for the possibility of an expanded campaign and harsh strikes against Gaza,” in a meeting with local leaders near the coastal territory.

Israel’s Magen David Adom emergency service said it had received no immediate reports of casualties.

Israel’s Iron Dome air defence system intercepted rockets above the coastal city of Ashkelon and elsewhere in the south, AFP photographers witnessed.

The latest violence comes a day after Israeli strikes on Gaza killed three top Islamic Jihad militants and 12 others, including four children, according to a health ministry toll.

Israel’s military said Wednesday’s strikes included firing on militants “who were travelling to a rocket launch site in the city of Khan Yunis” in southern Gaza.

Islamic Jihad had vowed Tuesday (9) to retaliate, with Israel warning its residents near the border to stay near bomb shelters.

Ahead of Wednesday’s exchange of fire, Gaza’s usually bustling shops were closed.

People in Gaza “expect the worst”, said resident Monther Abdullah.

“Everyone feels anxious and people aren’t on the street much. I definitely feel like there’s a war coming,” the 50-year-old told AFP.

Speaking in Ashkelon before the rocket fire, resident Amos Gueta, 58, said there was a feeling of both “anxiety and satisfaction that something is being done” against Palestinian militants.

The latest violence comes on the second anniversary of a devastating 11-day war fought between Gaza militants and Israel.

Hamas spokesman Abdul Latif al-Qanou said Wednesday “the strikes of the unified resistance are part of the process of responding to the massacre committed by (Israel).”

Both Hamas and Islamic Jihad are considered terrorist organizations by Israel and the United States.

Among those killed Tuesday were four children and three senior Islamic Jihad operatives.

The top militants were named as Jihad Ghannam, Khalil al-Bahtini and Tareq Ezzedine, a Gaza-based militant leader in the West Bank.

Earlier Wednesday, Israeli troops raided the West Bank town of Qabatiya, killing two people whom the army accused of firing at soldiers.

The Palestinian health ministry identified the two men as Ahmed Jamal Tawfiq Assaf, 19, and Rani Walid Ahmed Qatanat, 24.

The Israeli military said troops detained one person during the raid when soldiers were shot at from a vehicle.

“The soldiers responded with live fire toward the two assailants and killed them,” the army said.

Mourners including armed militants later carried the two men’s bodies through the streets in a funeral procession.

Israel has occupied the West Bank since the Six-Day War of 1967 and its forces regularly operate in Palestinian cities.

The Arab League on Wednesday condemned the “aggressive (and) barbaric Israeli raids on the Gaza Strip, which targeted civilians, children and women in residential neighbourhoods”.

The Gaza violence this week is the worst since a three-day escalation in August killed 49 Palestinians, with no Israeli fatalities.

Hamas chief Ismail Haniyeh spoke Wednesday to Qatar, Egypt and the United Nations, key mediators in Gaza, his spokesman Taher al-Nunu said.

While Hamas has fought multiple wars with Israel in recent years, the group stayed on the sidelines of last year’s conflict fought between Israel and Islamic Jihad.

The latest violence brings to 132 the number of Palestinians killed in the Israeli-Palestinian conflict so far this year.

Nineteen Israelis, one Ukrainian and one Italian have been killed over the same period, according to an AFP count based on official sources from the two sides.

These figures include combatants as well as civilians, and, on the Israeli side, three members of the country’s Arab minority.

-Agence France-Presse